Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.52 |
| ▸ | MIF | P14174 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11750270 | 0.85 | MIF (0.46) | CYP3A4TRPA1MIFALDH1A1HPGD | |
| SCHEMBL2046670 | 0.82 | MIF (0.65) | CYP3A4TRPA1MIFALDH1A1HPGD | |
| SCHEMBL21675914 | 0.80 | MIF (0.48) | CYP3A4TRPA1MIFALDH1A1HPGD | |
| SCHEMBL20027159 | 0.80 | MIF (0.55) | TRPA1MIFTAAR1SLC6A2GRIN1 | |
| SCHEMBL23130498 | 0.78 | MIF (0.56) | CYP3A4TRPA1MIFALDH1A1HPGD | |
| SCHEMBL23465177 | 0.78 | MIF (0.56) | CYP3A4TRPA1MIFALDH1A1HPGD | |
| SCHEMBL2766608 | 0.77 | MIF (0.54) | CYP3A4TRPA1MIFALDH1A1HPGD | |
| SCHEMBL11747524 | 0.75 | KIF11 (0.36) | CYP3A4TRPA1MIFALDH1A1HPGD | |
| SCHEMBL1883321 | 0.73 | MIF (0.50) | CYP3A4TRPA1MIFALDH1A1HPGD | |
| SCHEMBL15863522 | 0.73 | MIF (0.60) | CYP3A4TRPA1MIFALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11066495-B2 | Phosphaguanidine group IV metal olefin polymerization catalysts | DOW GLOBAL TECHNOLOGY LLC (US) | 2021-07-20 | — | — | US | disclosed |
| EP-3519470-B1 | PHOSPHAGUANIDINE GROUP IV METAL OLEFIN POLYMERIZATION CATALYSTS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2020-10-21 | — | — | EP | disclosed |
| US-20200031960-A1 | PHOSPHAGUANIDINE GROUP IV METAL OLEFIN POLYMERIZATION CATALYSTS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2020-01-30 | — | — | US | disclosed |
| US-4202786-A | Peroxygen bleaching and compositions therefor | FMC CORPORATION (US) | 1980-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11066495-B2 | Phosphaguanidine group IV metal olefin polymerization catalysts | POLG, ODC1, RNGTT | CYP3A4 779/4885TRPA1 1829/4885MIF 3138/4885 |
| US-20200031960-A1 | PHOSPHAGUANIDINE GROUP IV METAL OLEFIN POLYMERIZATION CATALYSTS | POLG, ODC1, RNGTT | CYP3A4 779/4885TRPA1 1829/4885MIF 3138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.