Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | ACACA | Q13085 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11857755 | 0.95 | ACACB (0.38) | RIPK1ACACBACACA | |
| SCHEMBL11850505 | 0.93 | ACACB (0.41) | RIPK1ACACBACACA | |
| SCHEMBL28413117 | 0.86 | — | — | |
| SCHEMBL3370879 | 0.78 | MEN1 (0.33) | RIPK1 | |
| SCHEMBL5800588 | 0.77 | RIPK1 (0.38) | RIPK1ACACBACACA | |
| SCHEMBL14293914 | 0.77 | ACACB (0.48) | RIPK1ACACBACACA | |
| SCHEMBL622595 | 0.75 | TRPV1 (0.32) | — | |
| SCHEMBL1658860 | 0.74 | RIPK1 (0.37) | RIPK1ACACBACACA | |
| SCHEMBL25927335 | 0.74 | RIPK1 (0.37) | RIPK1ACACBACACA | |
| SCHEMBL25927332 | 0.74 | RIPK1 (0.37) | RIPK1ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4188403-A | Cyclopentan-1-amines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-02-12 | — | — | US | disclosed |
| US-3932487-A | HYPOTENSIVE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-13 | — | — | US | disclosed |