SCHEMBL622595

SCHEMBL622595

[CH2]C(O)CCCCC([CH2])O

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 1/20 0.32
TRPA1 O75762 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11184288 0.87
SCHEMBL3388566 0.87
SCHEMBL28830462 0.84
SCHEMBL4929206 0.84 LMNA (0.48) TRPV1TRPA1
SCHEMBL28563966 0.84 TRPV1 (0.36) TRPV1TRPA1
SCHEMBL8459228 0.84 TRPV1 (0.31) TRPV1TRPA1
SCHEMBL8453338 0.84 TRPV1 (0.31) TRPV1TRPA1
SCHEMBL11163355 0.84 TRPV1 (0.31) TRPV1TRPA1
SCHEMBL8403266 0.84
SCHEMBL1565831 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2245003-A2 CONTRAST AGENTS GE Healthcare AS (NO) 2010-11-03 EP claimed
WO-2009106552-A2 CONTRAST AGENTS GE HEALTHCARE AS (NO) 2009-09-03 WO claimed
EP-0513300-B1 QUATERNARY CROSSLINKED ALLYLAMMONIUMPOLYMERS, PREPARATION AND USE THEREOF ZENECA LTD (GB) 1997-05-14 EP claimed
US-5589166-A Cross-linked quaternary ammonium derivatives of poly(N,N-dialkylallyl) ammonium polymers ZENECA LIMITED (GB) 1996-12-31 US claimed
EP-0740679-A1 CROSSLINKED POLYMERIC AMMONIUM SALTS E.I. DU PONT DE NEMOURS & COMPANY INCORPORATED (US) 1996-11-06 EP claimed
US-5556619-A BILE ACID SEQUESTERANTS TO LOWER BLOOD CHOLESTEROL, POLYAMINES THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1996-09-17 US claimed
WO-1995019384-A1 CROSSLINKED POLYMERIC AMMONIUM SALTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-07-20 WO claimed
EP-0513300-A1 QUATERNARY CROSSLINKED ALLYLAMMONIUMPOLYMERS, PREPARATION AND USE THEREOF. ICI PLC (GB) 1992-11-19 EP claimed
WO-1992010522-A1 QUATERNARY CROSSLINKED ALLYLAMMONIUMPOLYMERS, PREPARATION AND USE THEREOF IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-06-25 WO claimed
US-8535642-B2 Contrast agents GE HEALTHCARE AS (NO) 2013-09-17 US disclosed
US-20120039815-A9 CONTRAST AGENTS GE HEALTHCARE AS (NO) 2012-02-16 US disclosed
US-20110052504-A1 CONTRAST AGENTS GE HEALTHCARE AS (NO) 2011-03-03 US disclosed
EP-2245003-A2 CONTRAST AGENTS GE Healthcare AS (NO) 2010-11-03 EP disclosed
WO-2010060941-A2 CONTRAST AGENTS GE HEALTHCARE AS (NO) 2010-06-03 WO disclosed
EP-0582324-A1 Heat transfer sheet DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) 1994-02-09 EP disclosed
US-5223476-A HEAT TRANSFER SHEET DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) 1993-06-29 US disclosed
EP-0513300-A1 QUATERNARY CROSSLINKED ALLYLAMMONIUMPOLYMERS, PREPARATION AND USE THEREOF. ICI PLC (GB) 1992-11-19 EP disclosed
WO-1992010522-A1 QUATERNARY CROSSLINKED ALLYLAMMONIUMPOLYMERS, PREPARATION AND USE THEREOF IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-06-25 WO disclosed
US-5106815-A Heat transfer sheet DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) 1992-04-21 US disclosed
EP-0427867-A1 THERMAL TRANSFER SHEET DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) 1991-05-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120039815-A9 CONTRAST AGENTS C5, TXN, CBR3 TRPV1 2122/4885TRPA1 762/4885
US-20110052504-A1 CONTRAST AGENTS C5, TXN, CBR3 TRPV1 2122/4885TRPA1 762/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.