Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.51 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.51 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11444690 | 0.92 | CYP19A1 (0.47) | ALDH1A1MAPTTSHRHPGDCYP1A2 | |
| SCHEMBL11465439 | 0.90 | CYP19A1 (0.54) | ALDH1A1MAPTTSHRHPGDCYP1A2 | |
| SCHEMBL11393260 | 0.88 | CYP19A1 (0.45) | ALDH1A1MAPTTSHRHPGDCYP1A2 | |
| SCHEMBL11425566 | 0.87 | CYP19A1 (0.39) | ALDH1A1MAPTTSHRHPGDCYP1A2 | |
| SCHEMBL11438244 | 0.82 | PDE4B (0.42) | ALDH1A1CYP19A1LMNAMEN1KMT2A | |
| SCHEMBL11423886 | 0.78 | ALDH1A1 (0.52) | ALDH1A1MAPTTSHRCYP3A4CYP19A1 | |
| SCHEMBL11228340 | 0.77 | ALDH1A1 (0.51) | ALDH1A1MAPTTSHRHPGDCYP1A2 | |
| SCHEMBL11228351 | 0.77 | ALDH1A1 (0.51) | ALDH1A1MAPTTSHRHPGDCYP1A2 | |
| SCHEMBL11380534 | 0.75 | ALDH1A1 (0.50) | ALDH1A1MAPTTSHRHPGDCYP1A2 | |
| SCHEMBL10529985 | 0.74 | CYP19A1 (0.61) | ALDH1A1MAPTTSHRHPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0004315-B1 | 1.1-DIPHENYLETHENE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MICROBICIDES | CIBA-GEIGY AG (CH) | 1981-02-25 | — | — | EP | disclosed |
| US-4213990-A | FUNGICIDES | CIBA-GEIGY CORPORATION (US) | 1980-07-22 | — | — | US | disclosed |