Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.67 |
| ▸ | RAB9A | P51151 | 4/20 | 0.67 |
| ▸ | PPIB | P23284 | 1/20 | 0.62 |
| ▸ | PPIA | P62937 | 1/20 | 0.62 |
| ▸ | PPID | Q08752 | 1/20 | 0.62 |
| ▸ | PPIG | Q13427 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.60 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL6501301 | 0.88 | RAB9A (0.54) | NPC1RAB9APPIBPPIAPPID | |
| Maleic Acid SCHEMBL6501297 | 0.88 | RAB9A (0.54) | NPC1RAB9APPIBPPIAPPID | |
| SCHEMBL13149442 | 0.87 | TDP1 (0.77) | NPC1RAB9ASMN1; SMN2KDM4ETDP1 | |
| SCHEMBL8768843 | 0.85 | MAPT (0.62) | NPC1RAB9APPIBPPIAPPID | |
| SCHEMBL833589 | 0.85 | NPC1 (0.68) | NPC1RAB9ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL10528940 | 0.85 | KDM4E (0.66) | NPC1RAB9ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL26814829 | 0.84 | RAB9A (0.63) | NPC1RAB9ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL718603 | 0.84 | LMNA (0.56) | NPC1RAB9APPIBPPIAPPID | |
| SCHEMBL23099698 | 0.84 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2KDM4ETDP1 | |
| SCHEMBL10898232 | 0.84 | MEN1 (0.72) | NPC1RAB9ASMN1; SMN2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4225617-A | PSYCHOTROPIC AGENTS | LABORATOIRE L. LAFON (FR) | 1980-09-30 | — | — | US | disclosed |
| US-4209524-A | CENTRAL NERVOUS SYSTEM | LABORATOIRE L. LAFON (FR) | 1980-06-24 | — | — | US | disclosed |
| US-4209523-A | TREATMENT OF THE CENTRAL NERVOUS SYSTEM | LABORATOIRE L. LAFON (FR) | 1980-06-24 | — | — | US | disclosed |
| US-4183951-A | PSYCHOTROPIC AGENTS | LABORATOIRE L. LAFON (FR) | 1980-01-15 | — | — | US | disclosed |
| US-4152458-A | CENTRAL NERVOUS SYSTEM, PSYCHOTROPIC AGENTS | LABORATOIRE L. LAFON (FR) | 1979-05-01 | — | — | US | disclosed |
| US-4151300-A | CENTRAL NERVOUS SYSTEM, PSYCHOTROPIC | LABORATOIRE L. LAFON (FR) | 1979-04-24 | — | — | US | disclosed |
| US-4122186-A | PSYCHOTROPIC AGENTS | LABORATOIRE L. LAFON (FR) | 1978-10-24 | — | — | US | disclosed |