Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 8/20 | 0.67 |
| ▸ | PGR | P06401 | 4/20 | 0.66 |
| ▸ | AR | P10275 | 2/20 | 0.66 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.66 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 8/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | SHBG | P04278 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11430610 | 0.94 | PGR (0.69) | NR3C2PGRARCHRM1NR3C1 | |
| SCHEMBL11425678 | 0.92 | PGR (0.66) | NR3C2PGRARCHRM1NR3C1 | |
| SCHEMBL11431440 | 0.91 | HIF1A (0.66) | NR3C2PGRARCHRM1NR3C1 | |
| SCHEMBL11283513 | 0.90 | PGR (0.75) | NR3C2PGRARCHRM1NR3C1 | |
| SCHEMBL10534803 | 0.90 | NR3C2 (0.80) | NR3C2PGRARCHRM1NR3C1 | |
| SCHEMBL9789725 | 0.90 | NR3C2 (0.80) | NR3C2PGRARCHRM1NR3C1 | |
| SCHEMBL11441908 | 0.90 | NR3C2 (0.65) | NR3C2PGRARCHRM1NR3C1 | |
| SCHEMBL11431223 | 0.89 | NR3C2 (0.61) | NR3C2PGRARCHRM1NR3C1 | |
| SCHEMBL11121959 | 0.89 | PGR (0.62) | NR3C2PGRARCHRM1NR3C1 | |
| SCHEMBL11121960 | 0.89 | PGR (0.62) | NR3C2PGRARCHRM1NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4242334-A | ANTIINFLAMMATORY AGENTS; SKIN DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-12-30 | — | — | US | disclosed |