Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 8/20 | 0.80 |
| ▸ | PGR | P06401 | 4/20 | 0.80 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.80 |
| ▸ | HIF1A | Q16665 | 9/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | AR | P10275 | 2/20 | 0.70 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.55 |
| ▸ | SHBG | P04278 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10534803 | 1.00 | NR3C2 (0.80) | NR3C2PGRNR3C1HIF1AKMT2A | |
| SCHEMBL20829000 | 0.91 | NR3C2 (0.86) | NR3C2PGRNR3C1HIF1AKMT2A | |
| SCHEMBL605474 | 0.91 | NR3C2 (0.85) | NR3C2PGRNR3C1HIF1AKMT2A | |
| SCHEMBL11430610 | 0.90 | PGR (0.69) | NR3C2PGRNR3C1HIF1AKMT2A | |
| SCHEMBL11433013 | 0.90 | NR3C2 (0.67) | NR3C2PGRNR3C1HIF1AKMT2A | |
| Resocortol Butyrate SCHEMBL2110603 | 0.90 | NR3C2 (0.89) | NR3C2PGRNR3C1HIF1AKMT2A | |
| SCHEMBL11581184 | 0.90 | NR3C2 (0.89) | NR3C2PGRNR3C1HIF1AKMT2A | |
| SCHEMBL11581192 | 0.90 | NR3C2 (0.89) | NR3C2PGRNR3C1HIF1AKMT2A | |
| SCHEMBL11425678 | 0.89 | PGR (0.66) | NR3C2PGRNR3C1HIF1AKMT2A | |
| SCHEMBL4285504 | 0.89 | PGR (0.88) | NR3C2PGRNR3C1HIF1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021408-A | Administering antiinflammatory agents | JOUVEINAL S.A. (FR) | 1991-06-04 | — | — | US | disclosed |
| US-4933331-A | ANTIINFLAMMATORY AGENTS | JOUVEINAL, S.A. (FR) | 1990-06-12 | — | — | US | disclosed |
| US-4861765-A | 21-alkyl-, cycloalkyl- or aryl-substituted thio steroids and pharmaceutical compositions containing them | JOUVEINAL (FR) | 1989-08-29 | — | — | US | disclosed |
| EP-0208202-B1 | 21-SUBSTITUTED THIOSTEROIDS | JOUVEINAL S.A. (FR) | 1989-04-19 | — | — | EP | disclosed |
| EP-0208202-A1 | 21-Substituted thiosteroids | JOUVEINAL S.A. (FR) | 1987-01-14 | — | — | EP | disclosed |