Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 6/20 | 0.35 |
| ▸ | MME | P08473 | 2/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9814843 | 0.83 | CPB2 (0.59) | CPB2FOLH1CYP1A2 | |
| SCHEMBL6351551 | 0.78 | CPB2 (0.60) | CPB2MMEACECHRM1AKR1A1 | |
| SCHEMBL7439013 | 0.77 | CPB2 (0.61) | CPB2ACECHRM1AKR1A1CHRM3 | |
| Hydrochloric Acid SCHEMBL10549891 | 0.76 | CPB2 (0.58) | CPB2MMEACECHRM1AKR1A1 | |
| SCHEMBL6470771 | 0.74 | CPB2 (0.67) | CPB2CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL6470772 | 0.74 | CPB2 (0.67) | CPB2CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL489084 | 0.73 | CPB2 (0.51) | CPB2MMEACE | |
| SCHEMBL489085 | 0.73 | CPB2 (0.51) | CPB2MMEACE | |
| SCHEMBL12972552 | 0.73 | FOLH1 (0.65) | FOLH1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL12972560 | 0.73 | FOLH1 (0.65) | FOLH1CHRM1AKR1A1CHRM3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4228077-A | N-[2-(mercaptoalkyl)-3-mercaptoalkanoyl]-l-tryptophanes | E. R. SQUIBB & SONS, INC. (US) | 1980-10-14 | — | — | US | disclosed |
| US-4206121-A | ANGIOTENSIN, ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1980-06-03 | — | — | US | disclosed |
| US-4178291-A | HYPOTENSIVE AGENTS, ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1979-12-11 | — | — | US | disclosed |
| US-4176235-A | ANGIOTENSIN COVERTING ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1979-11-27 | — | — | US | disclosed |
| US-4175199-A | Substituted acyl derivatives of amino acids | E. R. SQUIBB & SONS, INC. (US) | 1979-11-20 | — | — | US | disclosed |
| US-4154936-A | ENZYME INHIBITORS, HYPOTENSIVE | E. R. SQUIBB & SONS, INC. (US) | 1979-05-15 | — | — | US | disclosed |
| US-4140864-A | ANGIOTENSIN CONVERTING ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1979-02-20 | — | — | US | disclosed |
| US-4116962-A | ANGIOTENSIN CONVERTING ENXYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1978-09-26 | — | — | US | disclosed |