SCHEMBL9814843

SCHEMBL9814843

CC(=O)SCC(CCC(=O)O)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CPB2 Q96IY4 1/20 0.59
FOLH1 Q04609 14/20 0.52
GRM3 Q14832 2/20 0.46
NAALAD2 Q9Y3Q0 1/20 0.46
CYP1A2 P05177 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11433451 0.83 CPB2 (0.54) CPB2FOLH1CYP1A2
SCHEMBL6351551 0.83 CPB2 (0.60) CPB2CYP1A2
SCHEMBL7439013 0.82 CPB2 (0.61) CPB2
SCHEMBL9814740 0.81 FOLH1 (0.48) CPB2FOLH1GRM3NAALAD2CYP1A2
SCHEMBL9814925 0.81 FOLH1 (0.56) CPB2FOLH1GRM3NAALAD2
Hydrochloric Acid SCHEMBL10549891 0.81 CPB2 (0.58) CPB2CYP1A2
SCHEMBL9814774 0.79 FOLH1 (0.50) CPB2FOLH1GRM3NAALAD2
SCHEMBL9814660 0.79 FOLH1 (0.50) CPB2FOLH1GRM3NAALAD2
SCHEMBL8573240 0.79 CPB2 (0.53) CPB2FOLH1
SCHEMBL9814887 0.79 FOLH1 (0.61) FOLH1GRM3NAALAD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4927966-A ANTITUMOR THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1990-05-22 US claimed
US-5010103-A Anticarcinogenic agents THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF N.Y. (US) 1991-04-23 US disclosed
US-4927966-A ANTITUMOR THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1990-05-22 US disclosed