Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | RARB | P10826 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9137911 | 0.93 | TSHR (0.48) | TSHRCYP3A4MAPTMEN1THRB | |
| SCHEMBL8766929 | 0.86 | LMNA (0.41) | TSHRCYP3A4LMNASMN1; SMN2ADRB2 | |
| SCHEMBL10353371 | 0.84 | TSHR (0.44) | TSHRCYP3A4MAPTMEN1THRB | |
| SCHEMBL2962642 | 0.84 | LMNA (0.36) | TSHRCYP3A4MAPTMEN1THRB | |
| SCHEMBL2721224 | 0.83 | TSHR (0.61) | TSHRCYP3A4MAPTMEN1THRB | |
| SCHEMBL15820283 | 0.80 | TSHR (0.44) | TSHRCYP3A4MAPTMEN1THRB | |
| SCHEMBL4838940 | 0.79 | TSHR (0.48) | TSHRCYP3A4MAPTMEN1THRB | |
| SCHEMBL7585280 | 0.79 | TSHR (0.48) | TSHRCYP3A4MAPTMEN1THRB | |
| SCHEMBL20825331 | 0.79 | TSHR (0.48) | TSHRCYP3A4MAPTMEN1THRB | |
| SCHEMBL3419111 | 0.79 | TSHR (0.48) | TSHRCYP3A4MAPTMEN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4214929-A | Liquid monopropellants containing dissolved combustion modifiers | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1980-07-29 | — | — | US | claimed |