Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | DDX3X | O00571 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11421989 | 0.92 | KCNMA1 (0.47) | KCNMA1ALDH1A1KMT2ASMN1; SMN2STAT3 | |
| SCHEMBL11430336 | 0.90 | KCNMA1 (0.48) | KCNMA1ALDH1A1KMT2ASMN1; SMN2STAT3 | |
| SCHEMBL11430407 | 0.88 | KCNMA1 (0.47) | KCNMA1ALDH1A1KMT2ASMN1; SMN2STAT3 | |
| Acetic Acid SCHEMBL11430476 | 0.87 | ALDH1A1 (0.46) | KCNMA1ALDH1A1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL11424281 | 0.86 | KCNMA1 (0.49) | KCNMA1ALDH1A1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL11422042 | 0.86 | KCNMA1 (0.48) | KCNMA1ALDH1A1KMT2ASMN1; SMN2STAT3 | |
| SCHEMBL11439444 | 0.85 | TTR (0.43) | KCNMA1ALDH1A1KMT2AHPGDMAPT | |
| SCHEMBL11425199 | 0.85 | KCNMA1 (0.43) | KCNMA1ALDH1A1KMT2ASMN1; SMN2STAT3 | |
| SCHEMBL11423138 | 0.85 | CYP1A2 (0.44) | KCNMA1ALDH1A1KMT2ASMN1; SMN2STAT3 | |
| SCHEMBL11433708 | 0.84 | MEN1 (0.48) | ALDH1A1KMT2ASMN1; SMN2HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |