Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD40 | P25942 | 3/20 | 0.63 |
| ▸ | CD40LG | P29965 | 3/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | TYMS | P04818 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11422168 | 0.89 | RAB9A (0.55) | CD40CD40LGRAB9AMAPTNPC1 | |
| SCHEMBL11439499 | 0.87 | CD40 (0.58) | CD40CD40LGRAB9AMAPTNPC1 | |
| SCHEMBL11425089 | 0.84 | CD40 (0.72) | CD40CD40LGRAB9AMAPTNPC1 | |
| SCHEMBL11440746 | 0.84 | CD40 (0.45) | CD40CD40LGPTPN11MEN1KMT2A | |
| SCHEMBL11430356 | 0.83 | MEN1 (0.54) | CD40CD40LGRAB9AMAPTNPC1 | |
| SCHEMBL11425195 | 0.83 | MAPT (0.50) | CD40CD40LGRAB9AMAPTNPC1 | |
| SCHEMBL11424407 | 0.83 | CD40 (0.57) | CD40CD40LGRAB9AMAPTNPC1 | |
| SCHEMBL11341346 | 0.83 | CD40 (0.52) | CD40CD40LGMEN1KMT2ACA1 | |
| SCHEMBL10908064 | 0.83 | CD40 (0.52) | CD40CD40LGPTPN11MEN1KMT2A | |
| SCHEMBL11432355 | 0.82 | CD40 (0.63) | CD40CD40LGRAB9AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |