Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.61 |
| ▸ | MEN1 | O00255 | 7/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | THRA | P10827 | 1/20 | 0.54 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11765604 | 0.89 | KMT2A (0.65) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL11434109 | 0.88 | CD40 (0.56) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL11430148 | 0.87 | KMT2A (0.58) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL11500868 | 0.85 | KMT2A (0.65) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL10908133 | 0.84 | MEN1 (0.64) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL11425866 | 0.84 | MEN1 (0.62) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL10907747 | 0.83 | ENPP2 (0.51) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL11342897 | 0.83 | KMT2A (0.53) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL11431261 | 0.83 | KMT2A (0.68) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL11442272 | 0.83 | MEN1 (0.60) | KMT2AMEN1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |