Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.58 |
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | THRA | P10827 | 1/20 | 0.51 |
| ▸ | TYMS | P04818 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.47 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.47 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.47 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.47 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11425189 | 0.88 | CD40 (0.53) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL11434100 | 0.87 | KMT2A (0.61) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL11765604 | 0.85 | KMT2A (0.65) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL11431303 | 0.84 | RAB9A (0.54) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL11426033 | 0.83 | KMT2A (0.58) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL11500868 | 0.83 | KMT2A (0.65) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL11341898 | 0.82 | TRPV1 (0.52) | KMT2AMEN1MAPTALDH1A1TRPV1 | |
| SCHEMBL11433027 | 0.82 | KAT6A (0.46) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL10909078 | 0.82 | MEN1 (0.50) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL11423038 | 0.81 | MEN1 (0.52) | KMT2AMEN1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |