Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11426600 | 0.93 | POLB (0.52) | POLBMAPTLMNAHTTMEN1 | |
| SCHEMBL11422986 | 0.92 | MEN1 (0.56) | POLBMAPTLMNAMEN1KMT2A | |
| SCHEMBL11423135 | 0.86 | POLB (0.51) | POLBMAPTLMNAHTTMEN1 | |
| SCHEMBL11423148 | 0.86 | POLB (0.51) | POLBMAPTLMNAHTTMEN1 | |
| SCHEMBL11343087 | 0.85 | TIMP3 (0.47) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL10907696 | 0.85 | CASP6 (0.44) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL11422993 | 0.85 | POLB (0.50) | POLBMAPTLMNAHTTMEN1 | |
| SCHEMBL11424280 | 0.85 | MAPT (0.51) | POLBMAPTLMNAHTTMEN1 | |
| SCHEMBL11421978 | 0.84 | MEN1 (0.52) | POLBMAPTLMNAHTTMEN1 | |
| SCHEMBL11425117 | 0.84 | MEN1 (0.49) | POLBMAPTLMNAHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |