Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.43 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.41 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.41 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.41 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11421866 | 0.92 | KCNMA1 (0.46) | KCNMA1KMT2AMEN1RAB9AP2RX1 | |
| SCHEMBL11425192 | 0.88 | KCNMA1 (0.44) | KCNMA1KMT2AMEN1RAB9AMAPT | |
| SCHEMBL11438365 | 0.87 | TNF (0.45) | KCNMA1KMT2AMEN1RAB9AMAPT | |
| SCHEMBL11428140 | 0.85 | PLAU (0.46) | KMT2AMEN1RAB9AP2RX1TNNI3 | |
| SCHEMBL11432089 | 0.84 | KCNMA1 (0.43) | KCNMA1KMT2AMEN1RAB9AP2RX1 | |
| SCHEMBL11425750 | 0.84 | KMT2A (0.42) | KCNMA1KMT2AMEN1RAB9AMAPT | |
| SCHEMBL11431542 | 0.84 | NT5E (0.55) | KCNMA1KMT2AMEN1RAB9AMAPT | |
| SCHEMBL11430407 | 0.84 | KCNMA1 (0.47) | KCNMA1KMT2AMEN1STAT3MAPT | |
| SCHEMBL11434200 | 0.83 | MEN1 (0.56) | KMT2AMEN1RAB9AMAPTPOLB | |
| SCHEMBL11215156 | 0.83 | NT5E (0.54) | KCNMA1KMT2AMEN1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |