Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD40 | P25942 | 3/20 | 0.50 |
| ▸ | CD40LG | P29965 | 3/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ATIC | P31939 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 2/20 | 0.40 |
| ▸ | TIMP3 | P35625 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11440724 | 0.88 | HSD17B10 (0.48) | CD40CD40LGENPP2HDAC1CYP1A2 | |
| SCHEMBL11350583 | 0.87 | CD40 (0.57) | CD40CD40LGENPP2CYP1A2ALDH1A1 | |
| SCHEMBL10908252 | 0.87 | CD40 (0.57) | CD40CD40LGENPP2ALDH1A1HSD17B10 | |
| SCHEMBL11500762 | 0.85 | CD40 (0.53) | CD40CD40LGENPP2CASP6CTDSP1 | |
| SCHEMBL11428597 | 0.84 | CD40 (0.45) | CD40CD40LGENPP2HDAC1CYP1A2 | |
| SCHEMBL11440899 | 0.84 | CD40 (0.45) | CD40CD40LGENPP2CYP1A2ALDH1A1 | |
| SCHEMBL19020654 | 0.84 | CD40 (0.69) | CD40CD40LGCASP6CTDSP1HDAC1 | |
| SCHEMBL11433131 | 0.84 | CD40 (0.69) | CD40CD40LGCASP6CTDSP1ALDH1A1 | |
| SCHEMBL11436100 | 0.82 | CD40 (0.49) | CD40CD40LGENPP2CASP6CTDSP1 | |
| SCHEMBL11426641 | 0.81 | CASP6 (0.46) | CD40CD40LGCASP6CTDSP1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216165-A | Amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |