Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11227410 | 0.88 | MEN1 (0.44) | KDM4EMEN1GAAKMT2AATM | |
| SCHEMBL9058079 | 0.86 | KDM4E (0.42) | KDM4EMEN1GAAKMT2AALDH1A1 | |
| SCHEMBL11434575 | 0.83 | LMNA (0.36) | KDM4EMEN1GAAKMT2AALDH1A1 | |
| SCHEMBL3466659 | 0.80 | KDM4E (0.49) | KDM4EMEN1GAAKMT2AATM | |
| SCHEMBL5794071 | 0.80 | KDM4E (0.49) | KDM4EMEN1GAAKMT2AATM | |
| SCHEMBL3466658 | 0.80 | KDM4E (0.49) | KDM4EMEN1GAAKMT2AATM | |
| SCHEMBL30776762 | 0.80 | KDM4E (0.49) | KDM4EMEN1GAAKMT2AATM | |
| SCHEMBL11434577 | 0.77 | KDM4E (0.45) | KDM4EMEN1GAAKMT2AATM | |
| SCHEMBL11489965 | 0.77 | SCN5A (0.33) | KDM4EMEN1GAAKMT2AATM | |
| Bromide SCHEMBL813723 | 0.72 | HTT (0.38) | KDM4EALDH1A1TDP1KCNH2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4224050-A | Chloroacetanilides having a selective herbicidal activity, ortho-alkenyl-substituted anilines, intermediates in the synthesis of said herbicidal chloroacetanilides, and methods for their preparation | MONTEDISON S.P.A. (IT) | 1980-09-23 | — | — | US | claimed |