Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11435587 | 0.86 | KDM4E (0.39) | KDM4EGAAADRB2ADRB1LMNA | |
| SCHEMBL11426324 | 0.83 | GAA (0.40) | KDM4EGAAADRB2ADRB1LMNA | |
| SCHEMBL5794071 | 0.82 | KDM4E (0.49) | KDM4EGAACYP2D6ALDH1A1TDP1 | |
| SCHEMBL3466658 | 0.82 | KDM4E (0.49) | KDM4EGAACYP2D6ALDH1A1TDP1 | |
| SCHEMBL30776762 | 0.82 | KDM4E (0.49) | KDM4EGAACYP2D6ALDH1A1TDP1 | |
| SCHEMBL3466659 | 0.82 | KDM4E (0.49) | KDM4EGAACYP2D6ALDH1A1TDP1 | |
| SCHEMBL6882581 | 0.82 | KDM4E (0.45) | KDM4ELMNACYP2D6SLC6A4HTR2B | |
| SCHEMBL8012133 | 0.82 | KDM4E (0.45) | KDM4ELMNACYP2D6SLC6A4HTR2B | |
| SCHEMBL4975113 | 0.82 | KDM4E (0.45) | KDM4ELMNACYP2D6SLC6A4HTR2B | |
| SCHEMBL11426326 | 0.77 | GAA (0.43) | KDM4EGAACYP1A2ALDH1A1GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0605363-B1 | Process for the preparation of 2-alkyl-6-methyl-N-(1'-methoxy-2'-propyl)-aniline and a process for the preparation of their chloracetanilides | CIBA GEIGY AG (CH) | 1996-06-12 | — | — | EP | claimed |
| US-5430188-A | Catalytic reductive alylation of 2-alkyl-6-methyl-aniline with methoxyacetone | CIBA-GEIGY CORPORATION (US) | 1995-07-04 | — | — | US | claimed |
| EP-0605363-A1 | Process for the preparation of 2-alkyl-6-methyl-N-(1'-methoxy-2'-propyl)-aniline and a process for the preparation of their chloracetanilides | CIBA-GEIGY AG (CH) | 1994-07-06 | — | — | EP | claimed |
| US-4224050-A | Chloroacetanilides having a selective herbicidal activity, ortho-alkenyl-substituted anilines, intermediates in the synthesis of said herbicidal chloroacetanilides, and methods for their preparation | MONTEDISON S.P.A. (IT) | 1980-09-23 | — | — | US | claimed |
| JP-6263700-A | — | — | None | — | — | JP | disclosed |
| EP-2892877-B1 | PROCESS FOR THE PREPARATION OF (S)-2-ETHYL-N-(1-METHOXYPROPAN -2-YL)-6-METHYL ANILINE | COUNCIL SCIENT IND RES (IN) | 2017-06-21 | — | — | EP | disclosed |
| US-9199930-B2 | Process for the preparation of (S)-2-ethyl-N-(1-methoxypropan-2-yl)-6-methyl aniline | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2015-12-01 | — | — | US | disclosed |
| US-20150225340-A1 | PROCESS FOR THE PREPARATION OF (S)-2-ETHYL-N-(1-METHOXYPROPAN -2-YL)-6-METHYL ANILINE | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2015-08-13 | — | — | US | disclosed |
| EP-2892877-A1 | PROCESS FOR THE PREPARATION OF (S)-2-ETHYL-N-(1-METHOXYPROPAN -2-YL)-6-METHYL ANILINE | Council of Scientific and Industrial Research (IN) | 2015-07-15 | — | — | EP | disclosed |
| WO-2014037962-A1 | PROCESS FOR THE PREPARATION OF (S)-2-ETHYL-N-(1-METHOXYPROPAN -2-YL)-6-METHYL ANILINE | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2014-03-13 | — | — | WO | disclosed |
| CN-1039994-C | Process for the preparation of 2-alkyl-6-methyl-N-(1'-methoxy-2'-propyl)-aniline and a process for the preparation of their chloracetanilides | NOVARTIS CO (CH) | 1998-09-30 | — | — | CN | disclosed |
| CN-1039994-C | Process for the preparation of 2-alkyl-6-methyl-N-(1'-methoxy-2'-propyl)-aniline and a process for the preparation of their chloracetanilides | NOVARTIS CO (CH) | 1998-09-30 | — | — | CN | disclosed |
| EP-0605363-B1 | Process for the preparation of 2-alkyl-6-methyl-N-(1'-methoxy-2'-propyl)-aniline and a process for the preparation of their chloracetanilides | CIBA GEIGY AG (CH) | 1996-06-12 | — | — | EP | disclosed |
| US-5430188-A | Catalytic reductive alylation of 2-alkyl-6-methyl-aniline with methoxyacetone | CIBA-GEIGY CORPORATION (US) | 1995-07-04 | — | — | US | disclosed |
| US-5430188-A | Catalytic reductive alylation of 2-alkyl-6-methyl-aniline with methoxyacetone | CIBA-GEIGY CORPORATION (US) | 1995-07-04 | — | — | US | disclosed |
| US-5430188-A | Catalytic reductive alylation of 2-alkyl-6-methyl-aniline with methoxyacetone | CIBA-GEIGY CORPORATION (US) | 1995-07-04 | — | — | US | disclosed |
| JP-H06263700-A | 2-ALKYL-6-METHYL-N-(1'-METHOXY-2'-PROPYL)ANILINE AND PREPARATION OF CHLOROACETANILIDE THEREOF | CIBA GEIGY AG | 1994-09-20 | — | — | JP | disclosed |
| EP-0605363-A1 | Process for the preparation of 2-alkyl-6-methyl-N-(1'-methoxy-2'-propyl)-aniline and a process for the preparation of their chloracetanilides | CIBA-GEIGY AG (CH) | 1994-07-06 | — | — | EP | disclosed |
| EP-0605363-A1 | Process for the preparation of 2-alkyl-6-methyl-N-(1'-methoxy-2'-propyl)-aniline and a process for the preparation of their chloracetanilides | CIBA-GEIGY AG (CH) | 1994-07-06 | — | — | EP | disclosed |
| EP-0605363-A1 | Process for the preparation of 2-alkyl-6-methyl-N-(1'-methoxy-2'-propyl)-aniline and a process for the preparation of their chloracetanilides | CIBA-GEIGY AG (CH) | 1994-07-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150225340-A1 | PROCESS FOR THE PREPARATION OF (S)-2-ETHYL-N-(1-METHOXYPROPAN -2-YL)-6-METHYL ANILINE | AZI2, HTR2A, HTR1B | KDM4E 205/4885GAA 4427/4885ADRB2 32/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.