Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 1/20 | 0.52 |
| ▸ | REN | P00797 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PSMB9 | P28065 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11435651 | 1.00 | CTRB1 (0.52) | CTRB1RENTSHRL3MBTL1PSMB9 | |
| SCHEMBL11587393 | 0.98 | CTRB1 (0.53) | CTRB1RENTSHRL3MBTL1PSMB9 | |
| SCHEMBL11434851 | 0.91 | CTRB1 (0.60) | CTRB1TSHRL3MBTL1KDM4ELMNA | |
| SCHEMBL11434855 | 0.91 | CTRB1 (0.60) | CTRB1TSHRL3MBTL1KDM4ELMNA | |
| SCHEMBL24513611 | 0.86 | CTRB1 (0.64) | CTRB1TSHRL3MBTL1KDM4ELMNA | |
| SCHEMBL7106091 | 0.86 | CTRB1 (0.64) | CTRB1TSHRL3MBTL1KDM4ELMNA | |
| SCHEMBL11167627 | 0.86 | CTRB1 (0.64) | CTRB1TSHRL3MBTL1KDM4ELMNA | |
| SCHEMBL11450738 | 0.86 | CTRB1 (0.64) | CTRB1TSHRL3MBTL1KDM4ELMNA | |
| SCHEMBL11167632 | 0.86 | CTRB1 (0.64) | CTRB1TSHRL3MBTL1KDM4ELMNA | |
| SCHEMBL11006653 | 0.86 | POLB (0.45) | PSMB9CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216209-A | Tripeptide angiotensin converting enzyme inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-08-05 | — | — | US | disclosed |