Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.56 |
| ▸ | PREP | P48147 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CTSK | P43235 | 2/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | PRCP | P42785 | 1/20 | 0.54 |
| ▸ | KDM1A | O60341 | 1/20 | 0.53 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11450738 | 1.00 | CTRB1 (0.64) | CTRB1NPSR1KMT2ATSHRL3MBTL1 | |
| SCHEMBL11167627 | 1.00 | CTRB1 (0.64) | CTRB1NPSR1KMT2ATSHRL3MBTL1 | |
| SCHEMBL7106091 | 1.00 | CTRB1 (0.64) | CTRB1NPSR1KMT2ATSHRL3MBTL1 | |
| SCHEMBL11167632 | 1.00 | CTRB1 (0.64) | CTRB1NPSR1KMT2ATSHRL3MBTL1 | |
| SCHEMBL11449038 | 0.94 | CTRB1 (0.58) | CTRB1NPSR1KMT2ATSHRL3MBTL1 | |
| SCHEMBL11449036 | 0.94 | CTRB1 (0.58) | CTRB1NPSR1KMT2ATSHRL3MBTL1 | |
| SCHEMBL11781980 | 0.93 | CTRB1 (0.63) | CTRB1NPSR1KMT2ATSHRL3MBTL1 | |
| SCHEMBL8055344 | 0.92 | CTRB1 (0.62) | CTRB1NPSR1KMT2ATSHRL3MBTL1 | |
| SCHEMBL7960529 | 0.92 | CTRB1 (0.55) | CTRB1NPSR1KMT2ATSHRL3MBTL1 | |
| SCHEMBL5319845 | 0.92 | CTRB1 (0.55) | CTRB1NPSR1KMT2ATSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220185855-A1 | NOVEL NON-OPIOID ANTI-PAIN MEDICATION | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2022-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220185855-A1 | NOVEL NON-OPIOID ANTI-PAIN MEDICATION | FGF1, OGFR, OPRL1 | CTRB1 3642/4885NPSR1 26/4885KMT2A 4193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.