SCHEMBL1143578

SCHEMBL1143578

CCCCCCC(=O)COCC1CCCCC1

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 3/20 0.50
MAPT P10636 1/20 0.41
KMT2A Q03164 1/20 0.41
SPHK1 Q9NYA1 2/20 0.40
CYP1A2 P05177 1/20 0.39
CES2 O00748 1/20 0.39
LMNA P02545 1/20 0.38
PLA2G4B P0C869 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17061000 1.00 NAAA (0.50) NAAAMAPTKMT2ASPHK1CYP1A2
SCHEMBL1142760 1.00 NAAA (0.50) NAAAMAPTKMT2ASPHK1CYP1A2
SCHEMBL1142540 0.98 NAAA (0.47) NAAAMAPTKMT2ASPHK1CYP1A2
SCHEMBL1142598 0.98 NAAA (0.49) NAAAMAPTKMT2ASPHK1CES2
SCHEMBL2323420 0.98 NAAA (0.49) NAAAMAPTKMT2ASPHK1CES2
SCHEMBL2343251 0.98 NAAA (0.49) NAAAMAPTKMT2ASPHK1CES2
SCHEMBL1142465 0.97 NAAA (0.46) NAAAMAPTKMT2ASPHK1CYP1A2
SCHEMBL17330348 0.94 NAAA (0.41) NAAASPHK1CYP1A2LMNA
SCHEMBL1143138 0.92 NAAA (0.40) NAAAMAPTKMT2ASPHK1CYP1A2
SCHEMBL1143159 0.87 LMNA (0.42) NAAASPHK1CYP1A2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3204159-B1 PROCESS FOR PREPARING SPHERICAL POLYMERIZATION CATALYST COMPONENTS FOR USE IN OLEFIN POLYMERIZATIONS GRACE W R & CO (US) 2020-12-16 EP disclosed
CN-107207657-B Process for preparing spherical polymerization catalyst components for olefin polymerization 格雷斯公司 2020-03-03 CN disclosed
EP-2701843-B1 EMULSION PROCESS FOR IMPROVED LARGE SPHERICAL POLYPROPYLENE CATALYSTS W R GRACE & CO -CONN (US) 2017-11-29 EP disclosed
US-9714302-B2 Process for preparing spherical polymerization catalyst components for use in olefin polymerizations W. R. Grace & Co.—Conn. (US) 2017-07-25 US disclosed
US-9403924-B2 Process of production of large and spherical polymerization catalyst and use of same in olefin polymerizations BASF CORPORATION (US) 2016-08-02 US disclosed
US-20150361194-A1 PROCESS OF PRODUCTION OF LARGE AND SPHERICAL POLYMERIZATION CATALYST AND USE OF SAME IN OLEFIN POLYMERIZATIONS W. R. GRACE & CO.-CONN. 2015-12-17 US disclosed
EP-2701843-A1 EMULSION PROCESS FOR IMPROVED LARGE SPHERICAL POLYPROPYLENE CATALYSTS BASF Corporation (US) 2014-03-05 EP disclosed
US-8569195-B2 Internal and external donor compounds for olefin polymerization catalysts II BASF CORPORATION (US) 2013-10-29 US disclosed
WO-2012149360-A1 EMULSION PROCESS FOR IMPROVED LARGE SPHERICAL POLYPROPYLENE CATALYSTS BASF CORPORATION (US) 2012-11-01 WO disclosed
US-20110207901-A1 INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS II BASF CATALYSTS LLC (US) 2011-08-25 US disclosed
US-8003559-B2 Internal donor for olefin polymerization catalysts BASF CORPORATION (US) 2011-08-23 US disclosed
US-20110034651-A1 MIXED DONOR SYSTEM FOR HIGH MELT FLOW AND HIGH ACTIVITY BASF CATALYSTS LLC (US) 2011-02-10 US disclosed
US-20090286672-A1 INTERNAL DONOR FOR OLEFIN POLYMERIZATION CATALYSTS BASF CATALYSTS LLC (US) 2009-11-19 US disclosed