Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.42 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.42 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2730257 | 0.98 | HTT (0.57) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL5267993 | 0.98 | HTT (0.57) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL6269869 | 0.96 | MEN1 (0.60) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL5270551 | 0.95 | MEN1 (0.63) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL5265746 | 0.95 | MEN1 (0.63) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL472216 | 0.94 | TSHR (0.56) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL1575700 | 0.91 | TSHR (0.57) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL11436017 | 0.91 | TSHR (0.57) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL212883 | 0.91 | TSHR (0.57) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL6544683 | 0.91 | TSHR (0.57) | HTTMEN1THRBKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4194066-A | POLYMERIZING POLYOXYALKYLENE GLYCOL (METH)ACRYLATES | JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JP) | 1980-03-18 | — | — | US | disclosed |