Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTN3A1 | O00481 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.42 |
| ▸ | SQLE | Q14534 | 6/20 | 0.41 |
| ▸ | ICMT | O60725 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11436605 | 1.00 | BTN3A1 (0.44) | BTN3A1KMT2AMAPTMEN1CYP3A4 | |
| SCHEMBL7757953 | 0.83 | KMT2A (0.64) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL530928 | 0.83 | KMT2A (0.64) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL530927 | 0.83 | KMT2A (0.64) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL954111 | 0.83 | KMT2A (0.56) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL954112 | 0.83 | KMT2A (0.56) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL8702915 | 0.79 | SQLE (0.43) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL8702913 | 0.79 | SQLE (0.43) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL4671195 | 0.75 | KMT2A (0.50) | BTN3A1KMT2AMAPTMEN1CYP3A4 | |
| SCHEMBL15655770 | 0.75 | KMT2A (0.50) | BTN3A1KMT2AMAPTMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4199519-A | TREATMENT OF PEPTIC ULCERS | SANKYO COMPANY LIMITED (JP) | 1980-04-22 | — | — | US | disclosed |