Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.57 |
| ▸ | SQLE | Q14534 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | FNTA | P49354 | 2/20 | 0.52 |
| ▸ | FNTB | P49356 | 2/20 | 0.52 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL530927 | 1.00 | KMT2A (0.64) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL530928 | 1.00 | KMT2A (0.64) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL954111 | 0.96 | KMT2A (0.56) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL954112 | 0.96 | KMT2A (0.56) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| Squalene SCHEMBL27987791 | 0.87 | KMT2A (0.85) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL11436605 | 0.83 | BTN3A1 (0.44) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL11436601 | 0.83 | BTN3A1 (0.44) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL8702915 | 0.82 | SQLE (0.43) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL8702913 | 0.82 | SQLE (0.43) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL23802597 | 0.79 | KMT2A (1.00) | KMT2AMAPTMEN1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670317-B9 | EPOXYCYCLOHEXENEDIONE DERIVATIVE | KYOWA HAKKO KOGYO KK (JP) | 2001-03-14 | — | — | EP | disclosed |
| EP-0670317-B1 | EPOXYCYCLOHEXENEDIONE DERIVATIVE | KYOWA HAKKO KOGYO KK (JP) | 2000-03-08 | — | — | EP | disclosed |
| US-5565489-A | MICROBIOCIDES, ANTITUMOR AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1996-10-15 | — | — | US | disclosed |
| EP-0670317-A1 | EPOXYCYCLOHEXENEDIONE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1995-09-06 | — | — | EP | disclosed |