Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | ANPEP | P15144 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tocainide SCHEMBL15761 | 0.85 | ATM (0.57) | ATMHSP90AA1ANPEPDRD2HTR2A | |
| S-Tocainide SCHEMBL308742 | 0.85 | ATM (0.57) | ATMHSP90AA1ANPEPDRD2HTR2A | |
| Tocainide SCHEMBL9614374 | 0.84 | ATM (0.55) | ATMHSP90AA1ANPEPDRD2HTR2A | |
| Tocainide SCHEMBL122779 | 0.84 | ATM (0.55) | ATMHSP90AA1ANPEPDRD2HTR2A | |
| Tocainide SCHEMBL4338155 | 0.82 | ATM (0.54) | ATMHSP90AA1ANPEPDRD2HTR2A | |
| SCHEMBL12832472 | 0.81 | ATM (0.60) | ATMHSP90AA1ANPEPDRD2HTR2A | |
| Tocainide SCHEMBL27874301 | 0.81 | ATM (0.53) | ATMHSP90AA1ANPEPDRD2HTR2A | |
| SCHEMBL6356591 | 0.79 | ATM (0.58) | ATMHSP90AA1ANPEPDRD2HTR2A | |
| SCHEMBL6717081 | 0.78 | ANPEP (0.57) | ATMHSP90AA1ANPEPDRD2HTR2A | |
| SCHEMBL6718778 | 0.78 | ANPEP (0.57) | ATMHSP90AA1ANPEPDRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4218477-A | LONG LASTING ORAL AGENTS | ASTRA PHARMACEUTICAL PRODUCTS, INC. (US) | 1980-08-19 | — | — | US | claimed |