Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.57 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | LARS1 | Q9P2J5 | 3/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CIT | O14578 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6717081 | 1.00 | ANPEP (0.57) | ANPEPAAK1ATMLARS1HSP90AA1 | |
| SCHEMBL7853958 | 0.83 | ATM (0.49) | ANPEPATMHSP90AA1MEN1CYP1A2 | |
| SCHEMBL6719511 | 0.83 | ANPEP (0.59) | ANPEPAAK1LARS1MEN1KMT2A | |
| S-Tocainide SCHEMBL308742 | 0.81 | ATM (0.57) | ANPEPATMHSP90AA1MEN1CYP1A2 | |
| Tocainide SCHEMBL15761 | 0.81 | ATM (0.57) | ANPEPATMHSP90AA1MEN1CYP1A2 | |
| Tocainide SCHEMBL122779 | 0.80 | ATM (0.55) | ANPEPATMHSP90AA1MEN1CYP1A2 | |
| Tocainide SCHEMBL9614374 | 0.80 | ATM (0.55) | ANPEPATMHSP90AA1MEN1CYP1A2 | |
| SCHEMBL11436632 | 0.78 | ATM (0.54) | ANPEPATMHSP90AA1MEN1CYP1A2 | |
| Tocainide SCHEMBL4338155 | 0.78 | ATM (0.54) | ANPEPATMHSP90AA1MEN1CYP1A2 | |
| SCHEMBL26464135 | 0.77 | AAK1 (0.53) | AAK1MEN1KMT2ACIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040152740-A1 | Arylglycine derivatives for use as glycine transport inhibitors | NPS ALLELIX CORPORATION (CA) | 2004-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152740-A1 | Arylglycine derivatives for use as glycine transport inhibitors | SLC1A2, SLC6A7, SLC1A1 | ANPEP 522/4885AAK1 1409/4885ATM 3390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.