Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | MLYCD | O95822 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11434770 | 0.88 | MEN1 (0.39) | ALDH1A1KDM4ERAB9AMEN1NPC1 | |
| SCHEMBL11446547 | 0.87 | NPC1 (0.38) | ALDH1A1KDM4ERAB9AMEN1NPC1 | |
| SCHEMBL11465500 | 0.86 | KMT2A (0.37) | ALDH1A1KDM4ERAB9AMEN1NPC1 | |
| SCHEMBL11331266 | 0.84 | SMN1; SMN2 (0.41) | ALDH1A1KDM4ERAB9AMEN1NPC1 | |
| SCHEMBL11450504 | 0.84 | ALDH1A1 (0.36) | ALDH1A1KDM4ERAB9AMEN1NPC1 | |
| SCHEMBL11341133 | 0.83 | RAB9A (0.40) | ALDH1A1KDM4ERAB9AMEN1NPC1 | |
| SCHEMBL11550476 | 0.82 | RAB9A (0.39) | ALDH1A1KDM4ERAB9AMEN1NPC1 | |
| SCHEMBL11456934 | 0.81 | SMN1; SMN2 (0.34) | ALDH1A1KDM4ERAB9AMEN1NPC1 | |
| SCHEMBL11434897 | 0.79 | MEN1 (0.39) | ALDH1A1KDM4ERAB9AMEN1NPC1 | |
| SCHEMBL11341247 | 0.77 | NPC1 (0.36) | ALDH1A1KDM4ERAB9AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4217362-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1980-08-12 | — | — | US | disclosed |
| US-4212888-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1980-07-15 | — | — | US | disclosed |
| US-4128663-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1978-12-05 | — | — | US | disclosed |