Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 5/20 | 0.39 |
| ▸ | PPARA | Q07869 | 5/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4173742 | 0.86 | MME (0.44) | TSHRTP53ALDH1A1LMNAF2 | |
| SCHEMBL4182695 | 0.86 | MME (0.44) | TSHRTP53ALDH1A1LMNAF2 | |
| SCHEMBL4178228 | 0.86 | MME (0.44) | TSHRTP53ALDH1A1LMNAF2 | |
| SCHEMBL10566173 | 0.84 | TSHR (0.42) | TSHRTP53ALDH1A1LMNAF2 | |
| SCHEMBL11059105 | 0.84 | GAA (0.48) | TSHRTP53ALDH1A1MAPT | |
| SCHEMBL4819455 | 0.84 | GAA (0.48) | TSHRTP53ALDH1A1MAPT | |
| SCHEMBL10566164 | 0.84 | TSHR (0.42) | TSHRTP53ALDH1A1LMNAF2 | |
| SCHEMBL4582283 | 0.83 | MME (0.54) | PPARGTACR1 | |
| SCHEMBL27773632 | 0.80 | MTNR1A (0.44) | TSHRTP53ALDH1A1LMNAPPARG | |
| SCHEMBL27773634 | 0.80 | MTNR1A (0.44) | TSHRTP53ALDH1A1LMNAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4213969-A | Phosphonous acid derivatives, processes for their preparation and their use in combatting microorganisms | CIBA-GEIGY CORPORATION (US) | 1980-07-22 | — | — | US | disclosed |
| EP-0002039-A1 | Phosphonous acid derivatives, processes for their preparation and their use in combating microorganisms | CIBA-GEIGY AG (CH) | 1979-05-30 | — | — | EP | disclosed |