Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA6 | P23280 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29203954 | 0.78 | CA1 (0.48) | CA1CA4CA6ALDH1A1CA12 | |
| SCHEMBL6648576 | 0.78 | CA1 (0.48) | CA1CA4CA6ALDH1A1CA12 | |
| SCHEMBL6797860 | 0.74 | ALDH1A1 (0.38) | CA1CA4CA6ALDH1A1CA12 | |
| SCHEMBL4425921 | 0.74 | CA1 (0.48) | CA1CA4CA6ALDH1A1CA12 | |
| SCHEMBL9372764 | 0.74 | CA1 (0.48) | CA1CA4CA6ALDH1A1CA12 | |
| SCHEMBL29156445 | 0.68 | CA1 (0.42) | CA1CA4CA6ALDH1A1CA12 | |
| SCHEMBL23572345 | 0.66 | CA1 (0.48) | CA1CA4CA6ALDH1A1CA12 | |
| Benzene SCHEMBL27824443 | 0.64 | ALDH1A1 (0.95) | CA1CA4CA6ALDH1A1CA12 | |
| SCHEMBL2272041 | 0.63 | — | — | |
| Acetic Acid SCHEMBL16395773 | 0.61 | CA12 (0.77) | CA1CA4CA6ALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4230798-A | ANIMAL-ORIGINATED URICASE | MILES LABORATORIES, INC. (US) | 1980-10-28 | — | — | US | disclosed |
| US-4119405-A | A HYDRAZONE AND 4,5-DIHYDROXY-2,7-NAPHTHALENEDISULFONIC ACID OR 1-HYDROXY-2-NAPHTHALENESULFONIC ACID | MILES LABORATORIES, INC. (US) | 1978-10-10 | — | — | US | disclosed |
| US-3979262-A | COLORIMETRY | HOFFMANN-LA ROCHE INC. (US) | 1976-09-07 | — | — | US | disclosed |