Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA4 | P22748 | 3/20 | 0.48 |
| ▸ | CA6 | P23280 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA3 | P07451 | 2/20 | 0.48 |
| ▸ | CA5A | P35218 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.48 |
| ▸ | DAO | P14920 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6648576 | 0.78 | CA1 (0.48) | CA1CA4CA6ALDH1A1CA12 | |
| SCHEMBL4425921 | 0.78 | CA1 (0.48) | CA1CA4CA6ALDH1A1CA12 | |
| SCHEMBL29203954 | 0.78 | CA1 (0.48) | CA1CA4CA6ALDH1A1CA12 | |
| SCHEMBL11436968 | 0.74 | CA1 (0.44) | CA1CA4CA6ALDH1A1CA12 | |
| SCHEMBL29156445 | 0.72 | CA1 (0.42) | CA1CA4CA6ALDH1A1CA12 | |
| SCHEMBL6797860 | 0.71 | ALDH1A1 (0.38) | CA1CA4CA6ALDH1A1CA12 | |
| Benzene SCHEMBL27824443 | 0.68 | ALDH1A1 (0.95) | CA1CA4CA6ALDH1A1CA12 | |
| Bicarbonate SCHEMBL7000646 | 0.68 | CA12 (0.83) | CA1CA4CA6ALDH1A1CA12 | |
| Oxalic Acid SCHEMBL4424852 | 0.67 | CA12 (0.80) | CA1CA4CA6ALDH1A1CA12 | |
| Acetic Acid SCHEMBL16395773 | 0.65 | CA12 (0.77) | CA1CA4CA6ALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0315115-B1 | 1-acyl-2,3-dihydro-4(1H)-quinolinone-4-oxime derivatives, process for producing them and use thereof | MOCHIDA PHARM CO LTD (JP) | 1994-06-15 | — | — | EP | disclosed |
| US-5077410-A | Hypotensive agents, antiedemic agents and diuretics | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-31 | — | — | US | disclosed |
| EP-0243982-B1 | 1-ACYL-2,3-DIHYDRO-4(1H)-QUINOLINONE-4-OXIME DERIVATIVE, PROCESS FOR THE PRODUCTION THEREOF, PHARMACEUTICAL COMPOSITION AND INTERMEDIATES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1991-04-17 | — | — | EP | disclosed |
| US-4968680-A | HYPOTENSIVE, ANTIEDEMIC, DIURETIC | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1990-11-06 | — | — | US | disclosed |
| US-4839368-A | DIURETICS, HYPOTENSIVE AGENTS, ANTIEDEMIC AGENTS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1989-06-13 | — | — | US | disclosed |
| EP-0315115-A2 | 1-acyl-2,3-dihydro-4(1H)-quinolinone-4-oxime derivatives, process for producing them and use thereof | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1989-05-10 | — | — | EP | disclosed |
| WO-1987006580-A1 | 1-ACYL-2,3-DIHYDRO-4(1H)-QUINOLINONE-4-OXIME DERIVATIVES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1987-11-05 | — | — | WO | disclosed |
| EP-0243982-A1 | 1-acyl-2,3-dihydro-4(1H)-quinolinone-4-oxime derivative, process for the production thereof, pharmaceutical composition and intermediates | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1987-11-04 | — | — | EP | disclosed |