Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11429863 | 0.94 | MAPT (0.49) | MAPTGAAALDH1A1HPGDKDM4E | |
| SCHEMBL11430227 | 0.93 | HPGD (0.44) | MAPTGAAALDH1A1HPGDKDM4E | |
| SCHEMBL11435253 | 0.90 | KMT2A (0.48) | MAPTGAAALDH1A1HPGDNPC1 | |
| SCHEMBL11441559 | 0.89 | GAA (0.52) | MAPTGAAALDH1A1HPGDKDM4E | |
| SCHEMBL11435607 | 0.85 | HPGD (0.45) | MAPTGAAALDH1A1HPGDKDM4E | |
| SCHEMBL11426678 | 0.85 | RAB9A (0.47) | MAPTALDH1A1NPC1RORCLMNA | |
| SCHEMBL11437547 | 0.84 | ACACB (0.44) | MAPTGAANPC1ACACBLMNA | |
| SCHEMBL11441966 | 0.82 | KMT2A (0.51) | GAAALDH1A1HPGDNPC1LMNA | |
| SCHEMBL11435190 | 0.80 | SMN1; SMN2 (0.46) | MAPTGAAALDH1A1HPGDKDM4E | |
| SCHEMBL11437011 | 0.77 | RAB9A (0.48) | ALDH1A1NPC1LMNACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0017376-A1 | Phenylacetamide compounds and an analgesic composition containing them | KISSEI PHARMACEUTICAL CO. LTD (JP) | 1980-10-15 | — | — | EP | disclosed |