Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11441561 | 0.88 | KDM4E (0.46) | MEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL11436989 | 0.84 | MAPT (0.49) | ACACBCYP2D6CYP1A2CYP2C19LMNA | |
| SCHEMBL11435182 | 0.83 | ACACB (0.39) | ACACBLMNAKCNH2NPC1MAPT | |
| SCHEMBL11434849 | 0.82 | OPRM1 (0.54) | KCNH2OPRM1OPRD1OPRK1 | |
| SCHEMBL11429899 | 0.79 | ADRA1D (0.46) | CYP2D6CYP1A2LMNAMEN1KMT2A | |
| SCHEMBL11435585 | 0.78 | BCHE (0.53) | L3MBTL1MEN1KMT2AOPRM1OPRD1 | |
| SCHEMBL11429863 | 0.77 | MAPT (0.49) | ACACBCYP2D6CYP1A2CYP2C19LMNA | |
| SCHEMBL11436508 | 0.77 | ACACB (0.40) | ACACBKMT2AKCNH2NPC1MAPT | |
| SCHEMBL11430227 | 0.76 | HPGD (0.44) | ACACBLMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL11441559 | 0.73 | GAA (0.52) | CYP2D6CYP1A2CYP2C19LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0017376-A1 | Phenylacetamide compounds and an analgesic composition containing them | KISSEI PHARMACEUTICAL CO. LTD (JP) | 1980-10-15 | — | — | EP | disclosed |