Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11425998 | 0.93 | KCNMA1 (0.47) | KCNMA1NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL11425436 | 0.92 | KCNMA1 (0.44) | KCNMA1NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL11431311 | 0.92 | KCNMA1 (0.47) | KCNMA1NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL11423149 | 0.85 | KCNMA1 (0.45) | KCNMA1NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL11422994 | 0.84 | KCNMA1 (0.44) | KCNMA1NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL11137430 | 0.84 | APEX1 (0.55) | KCNMA1NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL11427533 | 0.83 | CASP6 (0.41) | NPC1RAB9ACYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL11433970 | 0.83 | CASP6 (0.41) | NPC1RAB9ACYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL11422990 | 0.83 | KCNMA1 (0.50) | KCNMA1NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL11436279 | 0.83 | PRMT1 (0.56) | KCNMA1RAB9APOLBALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |