Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | PGR | P06401 | 2/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | PDE4A | P27815 | 1/20 | 0.55 |
| ▸ | HRH1 | P35367 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29260299 | 0.81 | LMNA (0.60) | LMNAHPGDMAPK1ALDH1A1HTT | |
| SCHEMBL11431461 | 0.81 | HPGD (0.43) | LMNAHPGDMAPK1ALDH1A1HTT | |
| SCHEMBL2130325 | 0.75 | HPGD (0.63) | LMNAHPGDMAPK1ALDH1A1HTT | |
| SCHEMBL1030015 | 0.75 | ALDH1A1 (0.53) | LMNAHPGDMAPK1ALDH1A1CYP2D6 | |
| SCHEMBL2992457 | 0.74 | LMNA (0.49) | LMNAHPGDMAPK1ALDH1A1HTT | |
| SCHEMBL2874468 | 0.74 | ALDH1A1 (0.56) | HPGDMAPK1ALDH1A1HTTKMT2A | |
| SCHEMBL996990 | 0.73 | HPGD (0.74) | LMNAHPGDMAPK1ALDH1A1HTT | |
| SCHEMBL27850227 | 0.72 | HPGD (0.68) | LMNAHPGDMAPK1ALDH1A1HTT | |
| SCHEMBL9447781 | 0.72 | HPGD (0.59) | LMNAHPGDMAPK1ALDH1A1HTT | |
| SCHEMBL4191512 | 0.72 | LMNA (0.49) | LMNAHPGDMAPK1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4189409-A | LIGHT STABILIZERS, IN THE PRESENCE OF AN ACID CATALYST | ARGUS CHEMICAL CORPORATION (US) | 1980-02-19 | — | — | US | disclosed |