Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | NAAA | Q02083 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1940930 | 0.80 | LMNA (0.53) | LMNACES2CES1NAAAMAPK1 | |
| Hydrochloric Acid SCHEMBL30424145 | 0.79 | LMNA (0.52) | LMNACES2CES1NAAAMAPK1 | |
| SCHEMBL9821864 | 0.79 | PRKCI (0.44) | PPARGPPARAKDM4EHSP90AB1 | |
| SCHEMBL10726758 | 0.78 | SELL (0.53) | LMNAPPARGPPARAKDM4EALDH1A1 | |
| SCHEMBL2862125 | 0.78 | MAPT (0.49) | LMNAMAPK1KDM4EALDH1A1MEN1 | |
| SCHEMBL621111 | 0.77 | LMNA (0.53) | LMNACES2CES1MAPK1KDM4E | |
| SCHEMBL11439654 | 0.76 | LMNA (0.42) | LMNACES2CES1KDM4EALDH1A1 | |
| SCHEMBL29104744 | 0.76 | LMNA (0.42) | LMNACES2CES1PPARGPPARA | |
| SCHEMBL452704 | 0.76 | LMNA (0.49) | LMNACES2CES1PPARGPPARA | |
| SCHEMBL7041414 | 0.75 | LMNA (0.65) | LMNAKDM4EALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0028063-A1 | Phenol derivatives, processes for their preparation and pharmaceutical compositions containing them | GLAXO GROUP LIMITED (GB) | 1981-05-06 | — | — | EP | disclosed |