Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 9/20 | 0.81 |
| ▸ | NR3C1 | P04150 | 7/20 | 0.81 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.81 |
| ▸ | LMNA | P02545 | 5/20 | 0.81 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.81 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.81 |
| ▸ | HTR1A | P08908 | 1/20 | 0.81 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.81 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.81 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.66 |
| ▸ | AR | P10275 | 5/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Flunisolide Acetate SCHEMBL22171521 | 1.00 | PGR (0.81) | PGRNR3C1CYP3A4LMNAABCB11 | |
| Flunisolide Acetate SCHEMBL11318982 | 1.00 | PGR (0.81) | PGRNR3C1CYP3A4LMNAABCB11 | |
| Flunisolide Acetate SCHEMBL29647928 | 1.00 | PGR (0.81) | PGRNR3C1CYP3A4LMNAABCB11 | |
| SCHEMBL13368106 | 0.92 | PGR (0.83) | PGRNR3C1CYP3A4LMNAABCB11 | |
| SCHEMBL13491387 | 0.92 | PGR (0.83) | PGRNR3C1CYP3A4LMNAABCB11 | |
| SCHEMBL13181587 | 0.90 | PGR (0.80) | PGRNR3C1CYP3A4LMNAABCB11 | |
| SCHEMBL13491146 | 0.90 | PGR (0.80) | PGRNR3C1CYP3A4LMNAABCB11 | |
| SCHEMBL11865029 | 0.90 | PGR (0.80) | PGRNR3C1CYP3A4LMNAABCB11 | |
| SCHEMBL13341447 | 0.90 | PGR (0.80) | PGRNR3C1CYP3A4LMNAABCB11 | |
| SCHEMBL13595541 | 0.90 | PGR (0.80) | PGRNR3C1CYP3A4LMNAABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4207235-A | Selective epoxidation of steroidal bromohydrins | SYNTEX (U.S.A.) INC. (US) | 1980-06-10 | — | — | US | disclosed |