Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 9/20 | 0.81 |
| ▸ | NR3C1 | P04150 | 7/20 | 0.81 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.81 |
| ▸ | LMNA | P02545 | 5/20 | 0.81 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.81 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.81 |
| ▸ | HTR1A | P08908 | 1/20 | 0.81 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.81 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.81 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.66 |
| ▸ | AR | P10275 | 5/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Flunisolide Acetate SCHEMBL11439896 | 1.00 | PGR (0.81) | PGRNR3C1CYP3A4LMNAABCB11 | |
| Flunisolide Acetate SCHEMBL22171521 | 1.00 | PGR (0.81) | PGRNR3C1CYP3A4LMNAABCB11 | |
| Flunisolide Acetate SCHEMBL29647928 | 1.00 | PGR (0.81) | PGRNR3C1CYP3A4LMNAABCB11 | |
| SCHEMBL13368106 | 0.92 | PGR (0.83) | PGRNR3C1CYP3A4LMNAABCB11 | |
| SCHEMBL13491387 | 0.92 | PGR (0.83) | PGRNR3C1CYP3A4LMNAABCB11 | |
| SCHEMBL13181587 | 0.90 | PGR (0.80) | PGRNR3C1CYP3A4LMNAABCB11 | |
| SCHEMBL13491146 | 0.90 | PGR (0.80) | PGRNR3C1CYP3A4LMNAABCB11 | |
| SCHEMBL11865029 | 0.90 | PGR (0.80) | PGRNR3C1CYP3A4LMNAABCB11 | |
| SCHEMBL13341447 | 0.90 | PGR (0.80) | PGRNR3C1CYP3A4LMNAABCB11 | |
| SCHEMBL13595541 | 0.90 | PGR (0.80) | PGRNR3C1CYP3A4LMNAABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108135863-B | EGR1 targeting molecules for the treatment of inflammatory and hyperproliferative conditions | 特拉维夫医疗中心医学研究基础设施和保健服务基金会 | 2021-07-27 | — | — | CN | disclosed |
| US-10538551-B2 | Process for preparation of corticosteroids | CORAL DRUGS PVT. LTD. (IN) | 2020-01-21 | — | — | US | disclosed |
| CN-110678543-A | In vitro culture system and method of use | 耶达研究及发展有限公司 | 2020-01-10 | — | — | CN | disclosed |
| US-20190177361-A1 | NOVEL PROCESS FOR PREPARATION OF CORTICOSTEROIDS | CORAL DRUGS PVT. LTD. (IN) | 2019-06-13 | — | — | US | disclosed |
| US-10233210-B2 | Process for preparation of glucocorticoid steroids | CORAL DRUGS PVT. LTD. (IN) | 2019-03-19 | — | — | US | disclosed |
| US-20180002372-A1 | NOVEL PROCESS FOR PREPARATION OF GLUCOCORTICOID STEROIDS | CORAL DRUGS PVT. LTD. (IN) | 2018-01-04 | — | — | US | disclosed |
| US-4305936-A | SOLUBILIZERS CONSISTING OF FATTY ACID GLYCERIDES, COCAMIDOPROPYL BETAINE AND A GLYCOL | DERMIK LABORATORIES (US) | 1981-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10538551-B2 | Process for preparation of corticosteroids | HSD17B7, NR3C2, CYP21A2 | PGR 56/4885NR3C1 17/4885CYP3A4 99/4885 |
| US-20190177361-A1 | NOVEL PROCESS FOR PREPARATION OF CORTICOSTEROIDS | HSD17B7, NR3C2, CYP11B1 | PGR 53/4885NR3C1 18/4885CYP3A4 96/4885 |
| US-10233210-B2 | Process for preparation of glucocorticoid steroids | CYP21A2, NR3C2, NR3C1 | PGR 65/4885NR3C1 3/4885CYP3A4 52/4885 |
| US-20180002372-A1 | NOVEL PROCESS FOR PREPARATION OF GLUCOCORTICOID STEROIDS | NR3C2, NR3C1, CYP21A2 | PGR 64/4885NR3C1 2/4885CYP3A4 55/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.