Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PDE2A | O00408 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.31 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.31 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.30 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.30 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1721415 | 0.85 | PDE2A (0.51) | CYP17A1CYP2C9CYP2C19PDE2AALDH1A1 | |
| SCHEMBL23084284 | 0.81 | ALDH1A1 (0.49) | CYP2C9PDE2AALDH1A1 | |
| SCHEMBL6319027 | 0.79 | ACACB (0.45) | CYP17A1CYP2C9CYP2C19PDE2AALDH1A1 | |
| SCHEMBL10290335 | 0.78 | PDE2A (0.52) | CYP17A1CYP2C9CYP2C19PDE2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL2715124 | 0.76 | PDE2A (0.50) | CYP17A1CYP2C9CYP2C19PDE2AALDH1A1 | |
| SCHEMBL10894587 | 0.74 | CYP17A1 (0.46) | CYP17A1CYP2C9CYP2C19HPGDACACB | |
| SCHEMBL28615738 | 0.74 | PDE2A (0.51) | CYP17A1CYP2C9CYP2C19PDE2AALDH1A1 | |
| SCHEMBL6839350 | 0.73 | KDM4E (0.46) | CYP17A1CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL690324 | 0.72 | AOC3 (0.52) | CYP17A1CYP2C9CYP2C19ALDH1A1AOC3 | |
| SCHEMBL13859551 | 0.72 | CYP17A1 (0.45) | CYP17A1CYP2C9CYP2C19PDE2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4194899-A | HERBICIDES, FUNGICIDES, PLANT GROWTH REGULATORS | ELI LILLY AND COMPANY (US) | 1980-03-25 | — | — | US | disclosed |
| US-4110099-A | INHIBITOR FOR INTERNODEL GROWTH OF PLANTS | ELI LILLY AND COMPANY (US) | 1978-08-29 | — | — | US | disclosed |
| US-4043791-A | Method of regulating the growth of aquatic weeds with pyridine derivatives | ELI LILLY AND COMPANY (US) | 1977-08-23 | — | — | US | disclosed |
| US-RE29367-E | HERBICIDES, FUNGICIDES, 5-PYRIMIDINYL | ELI LILLY AND COMPANY (US) | 1977-08-23 | — | — | US | disclosed |
| US-4002628-A | HERBICIDES, PLANT FUNGICIDES, PLANT GROWTH REGULATORS | ELI LILLY AND COMPANY (US) | 1977-01-11 | — | — | US | disclosed |
| US-3967949-A | Fluoroalkoxyphenyl-substituted nitrogen heterocycles as plant stunting agents | ELI LILLY AND COMPANY (US) | 1976-07-06 | — | — | US | disclosed |