Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 4/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18625781 | 0.85 | HDAC1 (0.32) | HDAC2HDAC8HDAC6HDAC1 | |
| SCHEMBL10792757 | 0.83 | HDAC1 (0.36) | HDAC2HDAC8HDAC6HDAC1 | |
| SCHEMBL6935159 | 0.81 | PPARD (0.47) | — | |
| SCHEMBL18161031 | 0.76 | GABBR2 (0.45) | HDAC2HDAC8HDAC6HDAC1 | |
| Fosmidomycin SCHEMBL301404 | 0.75 | TYMS (0.48) | — | |
| SCHEMBL6537250 | 0.75 | LPAR3 (0.46) | — | |
| Fosmidomycin SCHEMBL11438018 | 0.74 | TYMS (0.46) | — | |
| Fosmidomycin SCHEMBL4432380 | 0.74 | TYMS (0.46) | — | |
| SCHEMBL11437191 | 0.73 | — | — | |
| Fosmidomycin SCHEMBL14485270 | 0.73 | S1PR2 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4182758-A | BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-01-08 | — | — | US | claimed |
| US-4206156-A | ANTIMICROBIAL | FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1980-06-03 | — | — | US | disclosed |
| US-4182758-A | BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-01-08 | — | — | US | disclosed |