Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 6/20 | 0.35 |
| ▸ | NAAA | Q02083 | 2/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 4/20 | 0.32 |
| ▸ | PPARD | Q03181 | 4/20 | 0.32 |
| ▸ | PPARA | Q07869 | 4/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.32 |
| ▸ | TLR2 | O60603 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11440999 | 1.00 | PRKCA (0.35) | PRKCANAAAFFAR4FFAR1PPARG | |
| SCHEMBL11447551 | 1.00 | PRKCA (0.35) | PRKCANAAAFFAR4FFAR1PPARG | |
| SCHEMBL11440112 | 1.00 | PRKCA (0.35) | PRKCANAAAFFAR4FFAR1PPARG | |
| SCHEMBL11440691 | 0.99 | PRKCA (0.33) | PRKCANAAAFFAR4FFAR1TSHR | |
| SCHEMBL11535644 | 0.95 | PRKCA (0.38) | PRKCANAAAMEN1KMT2A | |
| SCHEMBL11620440 | 0.95 | PRKCA (0.38) | PRKCANAAAMEN1KMT2A | |
| SCHEMBL11533957 | 0.94 | PRKCA (0.36) | PRKCANAAA | |
| SCHEMBL11529993 | 0.91 | PRKCA (0.43) | PRKCANAAAMEN1KMT2A | |
| SCHEMBL11447573 | 0.91 | HTT (0.31) | — | |
| SCHEMBL11528587 | 0.90 | EPHX2 (0.36) | PRKCANAAATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4191682-A | Hindered piperidine carboxylic acids, metal salts thereof and stabilized compositions | CIBA-GEIGY CORPORATION (US) | 1980-03-04 | — | — | US | claimed |
| US-4191682-A | Hindered piperidine carboxylic acids, metal salts thereof and stabilized compositions | CIBA-GEIGY CORPORATION (US) | 1980-03-04 | — | — | US | disclosed |
| US-4191682-A | Hindered piperidine carboxylic acids, metal salts thereof and stabilized compositions | CIBA-GEIGY CORPORATION (US) | 1980-03-04 | — | — | US | disclosed |
| US-4116933-A | Hindered piperidine carboxylic acids, metal salts thereof and stabilized compositions | CIBA-GEIGY CORPORATION (US) | 1978-09-26 | — | — | US | disclosed |
| US-4116933-A | Hindered piperidine carboxylic acids, metal salts thereof and stabilized compositions | CIBA-GEIGY CORPORATION (US) | 1978-09-26 | — | — | US | disclosed |