SCHEMBL11535644

SCHEMBL11535644

CCC1(C)CC(OC(=O)CCCCCCCCC(=O)OC2CC(C)(CC)NC(C)(CC)C2C)C(C)C(C)(CC)N1

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 6/20 0.38
NAAA Q02083 2/20 0.36
LMNA P02545 2/20 0.30
KDM4E B2RXH2 1/20 0.30
DUSP3 P51452 1/20 0.30
EPHX2 P34913 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11620440 1.00 PRKCA (0.38) PRKCANAAALMNAKDM4EDUSP3
SCHEMBL11533957 0.99 PRKCA (0.36) PRKCANAAA
SCHEMBL11529993 0.96 PRKCA (0.43) PRKCANAAALMNAKDM4EDUSP3
SCHEMBL11440112 0.95 PRKCA (0.35) PRKCANAAAMEN1KMT2A
SCHEMBL11440896 0.95 PRKCA (0.35) PRKCANAAAMEN1KMT2A
SCHEMBL11447551 0.95 PRKCA (0.35) PRKCANAAAMEN1KMT2A
SCHEMBL11440999 0.95 PRKCA (0.35) PRKCANAAAMEN1KMT2A
SCHEMBL11528587 0.95 EPHX2 (0.36) PRKCANAAALMNAEPHX2
SCHEMBL11440691 0.94 PRKCA (0.33) PRKCANAAA
SCHEMBL11533627 0.93

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4141883-A Stabilization of synthetic polymers by penta-or-hexa-substituted 4-piperidinol derivatives SANKYO COMPANY, LIMITED (JP) 1979-02-27 US disclosed
US-4075165-A 2,2,6,6-TETRA-SUBSTITUTED-4-PIPERIDINOL CIBA-GEIGY CORPORATION (US) 1978-02-21 US disclosed