Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 3/20 | 0.73 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.73 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.60 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.52 |
| ▸ | NSD2 | O96028 | 2/20 | 0.51 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.51 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.51 |
| ▸ | NT5E | P21589 | 3/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11433774 | 0.93 | CASP6 (0.64) | CASP6CTDSP1PRMT1ENPP2NSD2 | |
| SCHEMBL11204758 | 0.92 | CASP6 (0.62) | CASP6CTDSP1PRMT1ENPP2NSD2 | |
| SCHEMBL11426163 | 0.91 | CASP6 (0.73) | CASP6CTDSP1PRMT1ENPP2NSD2 | |
| SCHEMBL11338243 | 0.86 | PRMT1 (0.66) | CASP6CTDSP1PRMT1ENPP2NSD2 | |
| SCHEMBL10907672 | 0.86 | CASP6 (0.65) | CASP6CTDSP1PRMT1ENPP2NSD2 | |
| SCHEMBL11435460 | 0.86 | CASP6 (0.54) | CASP6CTDSP1PRMT1ENPP2NSD2 | |
| SCHEMBL7890022 | 0.85 | CASP6 (0.78) | CASP6CTDSP1PRMT1ENPP2NSD2 | |
| SCHEMBL2184239 | 0.85 | CASP6 (1.00) | CASP6CTDSP1PRMT1ENPP2NSD2 | |
| SCHEMBL29495050 | 0.85 | CASP6 (1.00) | CASP6CTDSP1PRMT1ENPP2NSD2 | |
| SCHEMBL11428914 | 0.84 | CASP6 (0.64) | CASP6CTDSP1PRMT1ENPP2NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216165-A | Amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |