Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 2/20 | 0.60 |
| ▸ | TIMP3 | P35625 | 4/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.46 |
| ▸ | FGF1 | P05230 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 2/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | CD40 | P25942 | 1/20 | 0.45 |
| ▸ | CD40LG | P29965 | 1/20 | 0.45 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11438960 | 0.93 | PRMT1 (0.53) | PRMT1TIMP3SIRT1ENPP2FGF1 | |
| SCHEMBL11432539 | 0.85 | CASP6 (0.51) | PRMT1TIMP3ENPP2FGF1CASP6 | |
| SCHEMBL11432335 | 0.85 | TIMP3 (0.52) | PRMT1TIMP3SIRT1ENPP2FGF1 | |
| SCHEMBL11432534 | 0.84 | CASP6 (0.50) | PRMT1TIMP3ENPP2FGF1CASP6 | |
| SCHEMBL11418759 | 0.84 | TIMP3 (0.54) | PRMT1TIMP3SIRT1ENPP2FGF1 | |
| SCHEMBL11438340 | 0.84 | TIMP3 (0.54) | PRMT1TIMP3SIRT1ENPP2FGF1 | |
| SCHEMBL11437677 | 0.82 | CASP6 (0.44) | PRMT1CASP6CD40CD40LGNT5E | |
| SCHEMBL11437668 | 0.81 | CASP6 (0.43) | PRMT1CASP6CD40CD40LGNT5E | |
| SCHEMBL10900256 | 0.81 | PRMT1 (0.63) | PRMT1TIMP3SIRT1ENPP2FGF1 | |
| SCHEMBL11596825 | 0.81 | TIMP3 (0.67) | PRMT1TIMP3SIRT1ENPP2FGF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4229584-A | Ureylenebis(anionic substituted phenylene carbonyl)imino naphthalene sulfonic acids and naphthalene carboxylic acids and their salts | AMERICAN CYANAMID COMPANY (US) | 1980-10-21 | — | — | US | disclosed |
| US-4177209-A | COMPLEMENT INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1979-12-04 | — | — | US | disclosed |
| US-4129590-A | INHIBITORS OF THE COMPLEMENT SYSTEM | AMERICAN CYANAMID COMPANY (US) | 1978-12-12 | — | — | US | disclosed |