⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28883808 | 0.81 | GABRR1 (0.39) | — | |
| SCHEMBL9645822 | 0.80 | — | — | |
| SCHEMBL27523383 | 0.79 | — | — | |
| SCHEMBL248665 | 0.78 | SOAT1 (0.39) | — | |
| SCHEMBL5427965 | 0.78 | ALDH1A1 (0.36) | — | |
| SCHEMBL614185 | 0.78 | SOAT1 (0.39) | — | |
| SCHEMBL12987802 | 0.77 | — | — | |
| SCHEMBL12986226 | 0.77 | — | — | |
| SCHEMBL28071633 | 0.77 | — | — | |
| SCHEMBL4062275 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108129330-A | A kind of cyclopropylamine continuous production system and production method | 浙江沙星科技有限公司 | 2018-06-08 | — | — | CN | claimed |
| CN-104402782-B | The synthetic method of 2-[(4-dodecyloxy phenyl) sulfuryl] butyric acid | JIANGXI RENMING PHARMACEUTICAL CHEMICAL INDUSTRY CO., LTD. (CN) | 2016-01-27 | — | — | CN | claimed |
| CN-104402782-A | 2-[(4-dodecyloxy phenyl) sulfuryl] butyric acid synthetic method | JIANGXI RENMING MEDICINE CHEMICAL CO LTD | 2015-03-11 | — | — | CN | claimed |
| CN-108383798-A | Phthalazinone derivatives prodrug or its pharmaceutically acceptable salt and its pharmaceutical composition and application | 上海博邦医药科技有限公司 | 2018-08-10 | — | — | CN | disclosed |
| CN-108129330-A | A kind of cyclopropylamine continuous production system and production method | 浙江沙星科技有限公司 | 2018-06-08 | — | — | CN | disclosed |
| CN-107721850-A | A kind of preparation method of cyclopropylamine intermediate γ chloro methyl butyrates | 山东国邦药业股份有限公司 | 2018-02-23 | — | — | CN | disclosed |
| CN-107721850-A | A kind of preparation method of cyclopropylamine intermediate γ chloro methyl butyrates | 山东国邦药业股份有限公司 | 2018-02-23 | — | — | CN | disclosed |
| CN-107673973-A | A kind of preparation method of cyclopropylamine intermediate cyclopropanecarboxylic acid methyl esters | 山东国邦药业股份有限公司 | 2018-02-09 | — | — | CN | disclosed |
| CN-105906507-A | Ester cyclopropanecarboxylate solvent-free synthesis method | 成都化润药业有限公司 | 2016-08-31 | — | — | CN | disclosed |
| EP-3030233-A1 | OXAZOLE OREXIN RECEPTOR ANTAGONISTS | Merck Sharp & Dohme Corp. (US) | 2016-06-15 | — | — | EP | disclosed |
| CN-205088160-U | Gamma - chloro methyl butyrate's preparation facilities | SHANDONG GUOBANG PHARMACEUTICAL CO LTD | 2016-03-16 | — | — | CN | disclosed |
| EP-2185533-A2 | QUERCETIN DERIVATIVES AS ANTI-CANCER AGENTS | Dabur Pharma Limited (IN) | 2010-05-19 | — | — | EP | disclosed |
| WO-2009019721-A2 | QUERCETIN DERIVATIVES AS ANTI-CANCER AGENTS | DABUR PHARMA LIMITED (IN) | 2009-02-12 | — | — | WO | disclosed |
| CN-1199973-C | Substituted carbolnie metal complex and application thereof | SHANDONG SCIENCE & ENGINEERING (CN) | 2005-05-04 | — | — | CN | disclosed |
| CN-1472212-A | Substituted carbolnie metal complex and application thereof | 山东理工大学 | 2004-02-04 | — | — | CN | disclosed |
| EP-1133473-B1 | NEW MANUFACTURING PROCESS | ASTRAZENECA AB (SE) | 2003-04-09 | — | — | EP | disclosed |
| US-6350877-B1 | MANUFACTURE OF CLEVIDIPINE BY SALT FORMATION ESTERIFICATION | ASTRAZENECA AB (SE) | 2002-02-26 | — | — | US | disclosed |
| EP-1133473-A1 | NEW MANUFACTURING PROCESS | AstraZeneca AB (SE) | 2001-09-19 | — | — | EP | disclosed |
| WO-2000031035-A1 | NEW MANUFACTURING PROCESS | ASTRAZENECA AB (SE) | 2000-06-02 | — | — | WO | disclosed |
| EP-0174816-A2 | Biphenyl-based diester compounds and liquid crystal compositions containing same | AJINOMOTO CO., INC. (JP) | 1986-03-19 | — | — | EP | disclosed |