Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINA6 | P08185 | 4/20 | 0.63 |
| ▸ | SHBG | P04278 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.63 |
| ▸ | AR | P10275 | 5/20 | 0.51 |
| ▸ | PGR | P06401 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6241504 | 0.87 | SERPINA6 (0.67) | SERPINA6SHBGALDH1A1SLC22A1THRB | |
| SCHEMBL3452660 | 0.86 | SERPINA6 (0.65) | SERPINA6SHBGALDH1A1SLC22A1THRB | |
| SCHEMBL21405873 | 0.86 | SERPINA6 (0.65) | SERPINA6SHBGALDH1A1SLC22A1THRB | |
| SCHEMBL24102619 | 0.86 | SERPINA6 (0.65) | SERPINA6SHBGALDH1A1SLC22A1THRB | |
| SCHEMBL24102505 | 0.86 | SERPINA6 (0.65) | SERPINA6SHBGALDH1A1SLC22A1THRB | |
| SCHEMBL24102420 | 0.86 | SERPINA6 (0.65) | SERPINA6SHBGALDH1A1SLC22A1THRB | |
| SCHEMBL5501842 | 0.85 | SERPINA6 (0.64) | SERPINA6SHBGALDH1A1SLC22A1THRB | |
| SCHEMBL3452725 | 0.83 | SERPINA6 (0.61) | SERPINA6SHBGALDH1A1SLC22A1THRB | |
| SCHEMBL10946067 | 0.82 | SERPINA6 (0.60) | SERPINA6SHBGALDH1A1SLC22A1THRB | |
| SCHEMBL8536771 | 0.81 | SERPINA6 (0.58) | SERPINA6SHBGALDH1A1SLC22A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4191697-A | TRITIATED ESTRADIOLS | ROUSSEL UCLAF (FR) | 1980-03-04 | — | — | US | claimed |
| US-4191697-A | TRITIATED ESTRADIOLS | ROUSSEL UCLAF (FR) | 1980-03-04 | — | — | US | disclosed |