Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINA6 | P08185 | 4/20 | 0.67 |
| ▸ | SHBG | P04278 | 3/20 | 0.67 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | THRB | P10828 | 1/20 | 0.67 |
| ▸ | AR | P10275 | 5/20 | 0.54 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.46 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 3/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | SNCA | P37840 | 2/20 | 0.46 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24102505 | 0.89 | SERPINA6 (0.65) | SERPINA6SHBGSLC22A1ALDH1A1THRB | |
| SCHEMBL3452660 | 0.89 | SERPINA6 (0.65) | SERPINA6SHBGSLC22A1ALDH1A1THRB | |
| SCHEMBL24102619 | 0.89 | SERPINA6 (0.65) | SERPINA6SHBGSLC22A1ALDH1A1THRB | |
| SCHEMBL24102420 | 0.89 | SERPINA6 (0.65) | SERPINA6SHBGSLC22A1ALDH1A1THRB | |
| SCHEMBL21405873 | 0.89 | SERPINA6 (0.65) | SERPINA6SHBGSLC22A1ALDH1A1THRB | |
| SCHEMBL5501842 | 0.88 | SERPINA6 (0.64) | SERPINA6SHBGSLC22A1ALDH1A1THRB | |
| SCHEMBL11442368 | 0.87 | SERPINA6 (0.63) | SERPINA6SHBGSLC22A1ALDH1A1THRB | |
| SCHEMBL3452725 | 0.86 | SERPINA6 (0.61) | SERPINA6SHBGSLC22A1ALDH1A1THRB | |
| SCHEMBL10946067 | 0.85 | SERPINA6 (0.60) | SERPINA6SHBGSLC22A1ALDH1A1THRB | |
| SCHEMBL21950081 | 0.83 | SMN1; SMN2 (0.59) | SERPINA6SHBGSLC22A1ALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549292-A2 | PHARMACEUTICAL PREPARATIONS, USE OF SAID PREPARATIONS AND METHOD FOR INCREASING THE BIOAVAILABILITY OF MEDICAMENTS FOR PERORAL ADMINISTRATION | Schering Aktiengesellschaft (DE) | 2005-07-06 | — | — | EP | disclosed |
| US-20040223983-A1 | Pharmaceutical preparations, use of these preparations and process for increasing the biovailability of pharmaceutical substances to be administered perorally | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2004-11-11 | — | — | US | disclosed |
| WO-2004032897-A2 | PHARMACEUTICAL PREPARATIONS, USE OF SAID PREPARATIONS AND METHOD FOR INCREASING THE BIOAVAILABILITY OF MEDICAMENTS FOR PERORAL ADMINISTRATION | SCHERING AKTIENGESELLSCHAFT (DE) | 2004-04-22 | — | — | WO | disclosed |
| US-4031074-A | Process for the preparation of 11β-hydroxy-18-alkyl-estrane compounds | AKZONA INCORPORATED (US) | 1977-06-21 | — | — | US | disclosed |
| US-3998813-A | Process for the preparation of 11β-hydroxy-18-alkyl-estrane compounds | AKZONA INCORPORATED (US) | 1976-12-21 | — | — | US | disclosed |