Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINA6 | P08185 | 4/20 | 0.64 |
| ▸ | SHBG | P04278 | 3/20 | 0.64 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | AR | P10275 | 6/20 | 0.52 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.45 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 3/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | SNCA | P37840 | 2/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6241504 | 0.88 | SERPINA6 (0.67) | SERPINA6SHBGSLC22A1ALDH1A1THRB | |
| SCHEMBL3452660 | 0.87 | SERPINA6 (0.65) | SERPINA6SHBGSLC22A1ALDH1A1THRB | |
| SCHEMBL21405873 | 0.87 | SERPINA6 (0.65) | SERPINA6SHBGSLC22A1ALDH1A1THRB | |
| SCHEMBL24102619 | 0.87 | SERPINA6 (0.65) | SERPINA6SHBGSLC22A1ALDH1A1THRB | |
| SCHEMBL24102420 | 0.87 | SERPINA6 (0.65) | SERPINA6SHBGSLC22A1ALDH1A1THRB | |
| SCHEMBL24102505 | 0.87 | SERPINA6 (0.65) | SERPINA6SHBGSLC22A1ALDH1A1THRB | |
| SCHEMBL10946067 | 0.85 | SERPINA6 (0.60) | SERPINA6SHBGSLC22A1ALDH1A1THRB | |
| SCHEMBL11442368 | 0.85 | SERPINA6 (0.63) | SERPINA6SHBGSLC22A1ALDH1A1THRB | |
| SCHEMBL3452725 | 0.84 | SERPINA6 (0.61) | SERPINA6SHBGSLC22A1ALDH1A1THRB | |
| SCHEMBL10380172 | 0.83 | SERPINA6 (0.52) | SERPINA6SHBGSLC22A1ALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1226155-B1 | 18-NOR-STEROIDS AS SELECTIVELY ACTIVE ESTROGENS | BAYER SCHERING PHARMA AG (DE) | 2007-05-02 | — | — | EP | disclosed |
| US-20050282791-A1 | 18-nor steroids as selectively active estrogens | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2005-12-22 | — | — | US | disclosed |
| US-6958327-B1 | 18 Norsteroids as selectively active estrogens | SCHERING, AG (DE) | 2005-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050282791-A1 | 18-nor steroids as selectively active estrogens | GPER1, ESR2, ESRRA | SERPINA6 697/4885SHBG 11/4885SLC22A1 205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.