Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | FASN | P49327 | 2/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11465708 | 0.76 | CHRM2 (0.40) | CHRM2CHRM3MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11510578 | 0.73 | CHRM2 (0.38) | CHRM2CHRM3MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11341151 | 0.73 | MEN1 (0.40) | CHRM2CHRM3MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11455130 | 0.72 | MEN1 (0.39) | CHRM2CHRM3MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11443855 | 0.72 | CHRM3 (0.41) | CHRM2CHRM3MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11507066 | 0.71 | CHRM2 (0.44) | CHRM2CHRM3MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11341256 | 0.71 | MEN1 (0.43) | CHRM2CHRM3MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11442498 | 0.69 | MEN1 (0.33) | CHRM2CHRM3MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11442497 | 0.69 | MEN1 (0.33) | CHRM2CHRM3MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11437523 | 0.69 | MEN1 (0.33) | CHRM2CHRM3MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4217362-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1980-08-12 | — | — | US | disclosed |
| US-4212888-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1980-07-15 | — | — | US | disclosed |
| US-4128663-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1978-12-05 | — | — | US | disclosed |