Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 8/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 7/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 5/20 | 0.35 |
| ▸ | MERTK | Q12866 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11465708 | 0.74 | CHRM2 (0.40) | CHRM3CHRM2SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL11442496 | 0.72 | CHRM2 (0.37) | CHRM3CHRM2OPRD1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11510578 | 0.71 | CHRM2 (0.38) | CHRM3CHRM2SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL11341151 | 0.71 | MEN1 (0.40) | CHRM3CHRM2SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL11436157 | 0.67 | OPRM1 (0.36) | CHRM3CHRM2OPRD1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11341256 | 0.65 | MEN1 (0.43) | CHRM3CHRM2SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL11443811 | 0.63 | ALDH1A1 (0.39) | CHRM3CHRM5CHRM1CHRM2OPRD1 | |
| SCHEMBL11507066 | 0.63 | CHRM2 (0.44) | CHRM3CHRM2SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL11436426 | 0.62 | MLYCD (0.42) | CHRM3CHRM5CHRM1CHRM2OPRD1 | |
| SCHEMBL11437911 | 0.62 | RAB9A (0.37) | ALDH1A1AXLMERTKKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4217362-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1980-08-12 | — | — | US | disclosed |
| US-4212888-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1980-07-15 | — | — | US | disclosed |
| US-4128663-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1978-12-05 | — | — | US | disclosed |